Fluorochrome,  LLC



Major Publications

Balercia, G., Chen, S., and Bentivoglio, M., "Electron microscopic analysis of fluorescent neuronal labeling after photoconversion," Journal of Neuroscience Methods 45 (1992) 87-98.

*Pieribone, V.A., Aston-Jones, G., "The iontophoretic application of Flouro-Gold for the study of the afferents to deep brain nuclei," Brain Research 475 (1988) 259-271.

Reep, R.L., Baccala, M.J., Booth, M.P., and Goodwin, G.S., "Combined retrograde and anterograde tracing of neuronal connections: Fluoro-Gold and autoradiography," Journal of Neuroscience Methods, 23 (1988) 1-5.

Schmued, L., "Fluoro-Gold and 4-Acetamido-4'-isothiocyanostilbene-2,2'disulfonic Acid: Use of Substituted Stilbenes in Neuroanatomical Studies," Methods in Neurosciences, 3 (1990) 317-330.

*Schmued, L.C. and Fallon, J.H., "Fluoro-Gold: a fluorescent retrograde axonal tracer with numerous unique properties," Brain Research, 377 (1986) 147-154.

*Schmued, L.C., "Anti-retrograde and retrograde neuroanatomical tract tracing with fluorescent compounds," Neuroscience Protocols, 94-050-02 (1994) 1-15.

Van Bockstaele, E.J., Wright, A.M., Cestari, D.M., and Pickel, V.M., "Immunolabeling of retrogradely transported Fluoro-Gold: sensitivity and application to ultrastructural analysis of transmitter-specific mesolimbic circuitry," Journal of Neuroscience Methods, 55 (1994) 65-78.

*Bowyer, J.F., Gough, B., Broening, H.W., Newport, G.D., and Schmued, L., "Fluoro-Gold and Pentamidine Inhibit the In Vitro and In Vivo Release of Dopamine in the Striatum of Rat," The Journal of Pharmacology and Experimental Therapeutics, 266 (1993) 1066-1074.

*Chang, H.T., Kuo, H., Whittaker, J.A., and Cooper, N.G.F., "Light and electron microscopic analysis of projection neurons retrogradely labeled with Fluoro-Gold notes on the application of antibodies of Fluoro-Gold," Journal of Neuroscience Methods, 35 (1990) 31-37.

Schmued, L.C., Kyriakidis, K., Fallon, J.H., and Ribak, C.E., "Neurons containing retrogradely transported Fluoro-Gold exhibit a variety of iysosomal profiles: a combined brightfield, fluorescence and electron microscopic study," Journal of Neurocytology, 18 (1989) 333-343.

Schmued, L., Kyriakidis, K., & Heimer, L., In vivo anterograde and retrograde axonal transport of the fluorescent rhodamine-dextran-amine, Fluoro-Ruby, within the CNS. Brain Res, 526 (1990) 127-134.

Bowyer, J.F. and Schmued, L., Fluoro-Ruby labeling prior to an amphetamine neurotoxic insult shows a definitive massive loss of dopaminergic terminals and axons in caudateputamen. Brain Res., 1075, (2006) 236-239.

*KEY REFERENCES (See Medline database "Fluoro-Gold" for 1505 citations from July 1986 to November 2009, plus an additional 850 citations for "fluorogold" as of november 2009)

Notice: The original and only true Fluoro-Gold (Fluorogold) is produced by Fluorochrome, LLC and marketed by Fluorochrome, LLC and Histo-Chem Inc.

Fluoro-Gold (Fluorogold) is an exclusive product of Fluorochrome, LLC. It has been sold by Fluorochrome and widely used since 1985. Other companies are marketing a product they claim  is the same as or equivalent to Fluoro-Gold. In fact, the chemical structures of these compounds seem to be different from Fluoro-Gold. Certain physical properties of the compounds may be very different.

Fluoro-Gold, Antibody to Fluoro-Gold and Fluoro-Ruby are for investigational use only in laboratory research animals or for tests in vitro. NOT FOR USE IN HUMANS. These drugs should be used only by persons regularly engaged in conducting neuroanatomical studies and tests in vitro or in animals used only for laboratory research.

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